Summary: A study for males and females 18 through 70 years old with mild or moderate asthma.
The purpose of this study is to evaluate an oral investigational treatment for subjects with stable asthma. This study is open to male and female subjects 18 to 70 years old. Study participants will have 11 visits to a research center over approximately 30 weeks. Patients will be withdrawn from their current controller medication and enter a run-in phase. After completion of the run-in phase, patients will receive the investigational drug at 250 mcg or 500 mcg, or placebo.
All study-related medication, doctor visits and breathing tests will be provided. Study participants will be asked to complete a daily electronic diary to record their use of study medication and their asthma symptoms.
Patient Inclusion Criteria
Patients with the following may be eligible for the study.
· Men and women aged 18 through 70 years of age.
· The patient has received verbal and written study information.
· The patient has a diagnosis of persistent bronchial asthma.
· There has been no change in asthma treatment within 4 weeks prior to Visit 1.
· Patient is a non-smoker or ex-smoker (for 12 months or longer.)
· In the investigators judgment, the patient is able and willing to comply with study visits and procedures (including laboratory tests, lung function tests), plus accurate and timely completion of an electronic daily study diary.
Patient Exclusion Criteria
Patients with the following are not eligible for the study.
· Patients with poorly controlled asthma or exacerbation of asthma in the four weeks prior to Visit 1 (in the investigator's judgment).
· Patients who suffer from seasonal asthma alone.
· A history of lower airway infection in the four weeks prior to Visit 1.
· A diagnosis of chronic obstructive pulmonary disease (COPD) and/or other relevant lung disease.
· Abnormal laboratory values suggesting an undiagnosed disease, severe renal insufficiency, active hepatitis, or an HIV infection.
· A diagnosis, treatment or remission of any cancer (other than basal cell carcinoma) within two years prior to Visit 1.
· Patients with chronic heart failure.
· Suspected hypersensitivity and/or contraindication to the study medication or albuterol/salbutamol.
· Females who are pregnant or breast-feeding. Women of childbearing potential must practice adequate methods of birth control to prevent pregnancy during the study.
· Patients who have received any investigational medication or device in the month prior to Visit 1 or who plan to use another investigational medication during the study. Re-entry of a patient previously enrolled into the double blind portion of this trial (i.e., having passed Visit 3 and subsequently withdrawn).
· Patients, who have any other severe or acute or chronic medical or psychiatric conditions in the judgment of the investigator, would make the patient inappropriate for entry into this study.
· Spirometry results outside of the limits set by the study
This clinical trial is being done in many areas.

Contacts for some areas are:
Eliana Mendes, Study Coordinator
University of Miami School of Medicine
Room 7064-A
1600 Northwest 10th Avenue
Miami, FL 33101
Telephone: 305-243-2568
Fax: 305-243-6992

Barbara J Bahl, PhD, Study Coordinator
South Hills Pulmonary Associates, Inc.
Suite 306
1050 Bower Hill Road
Pittsburgh, PA 15243
Telephone: 412-942-0010; 412-572-6168
Fax: 412-344-6304

Jamie Plocky, Study Coordinator Brenda Melton, Study Coordinator
UCLA, David Geffen School of Medicine Mississippi Asthma and Allergy Clinic, PA
CHS32-79 Suites 201 and 101
10833 Le Conte Avenue 1600 North State Street
Los Angeles, CA 90095 Jackson, MS 39202
Telephone: 310-825-3806 Telephone: 601-354-4836
Fax: 310-206-5088 Fax: 601-354-4530

Brenda Melton, Study Coordinator
Mississippi Asthma and Allergy Clinic, PA
Suites 201 and 101
1600 North State Street
Jackson, MS 39202
Telephone: 601-354-4836
Fax: 601-354-4530

Summary: Asthma Research Study
Inclusion Criteria for Asthma Study:
· Non-smoking males and females between 12-75 years of age
· Diagnosis of asthma
· No change in asthma treatment for the last 4 weeks
· Good general health
· Study consists of 3 visits
· Investigation medication, study related lab tests, EKG and physical examinations included
· Reimbursement for time and travel
To see if you qualify, call or email The Clinical Research Center.
Contact:
The Clinical Research Center, LLC
1040 N. Mason Road, Suite 112
St. Louis, MO 63141
Telephone: 314-514-8509 or 888-343-1990
Email: recruitment@clinicalresearchcenter.com

Summary: Asthma- Safety of Oral Roflumilast
Mount Sinai School of Medicine is recruiting subjects to participate in an investigational study for a treatment for asthma.
You may participate in this study if you:
· Are 18 to 70 years old
· Have a diagnosis of asthma
· Are a non-smoker or ex-smoker (for 12 months or longer)
You may not participate in this study if you:
· Have poorly controlled asthma
· Suffer from seasonal asthma
· Have a diagnosis of COPD (chronic obstructive pulmonary disease)
· Have a history of HIV infection, active hepatitis or severe renal insufficiency
· Have a diagnosis, treatment or remission of any cancer
· Have chronic heart failure
Contact:
Katherine Barboza, Research Coordinator
Biomedical Research Alliance of New York
Mount Sinai School of Medicine
One Gustave L. Levy Place
New York, NY 10029
Telephone: 212-241-7521
Fax: 212-831-3560
Email: katherine.barboza@mssm.edu

Summary: Is Asthma taking your breath away?
If you are still symptomatic on your current medication, you may qualify for a research study evaluating an investigational medication for the treatment of asthma.
You will receive free:
· Study related medical care
· Lung function studies
· Laboratory work-up
· Electrocardiogram
· Study medication
· Compensation
Call now for more information if you of someone you know meet the following criteria:
· Between the ages of 12 to 75
· Except for asthma in good health
· Medical conditions must be stable
· Non-smoker for at least 1 full year
· Females on reliable method of birth control
· Medical records must be obtainable
Contact:
Commonwealth Clinical Research Specialists
2010 Bremo Road, S-115
Richmond, VA 23226
Telephone: 804-288-7425
Email: ccrs@richmondallergy.com

Summary: Adolescent/Adult Asthma Study.
Eligibility Criteria:
· Ages 12 and Up.
· Must have a 6-month history of Asthma prior to visit 1.
· FEV1 60-85% with 12% reversibility.
· Must be on stable regimen of daily ICS for at least 30 days prior to visit 1.
This is a device study using the new "Easy Breath" breath actuated device versus current HFA propelled device. Study lasts 12 weeks.
For more information, contact:
Patti Hall, RN, BSN, CCRC,
Director of Clinical Research
Family Allergy and Asthma Research Institute
Bluegrass Avenue Medical Plaza
1700 Bluegrass Avenue, Suite 400
Louisville, KY 40215
Telephone: 502-368-0732
Fax: 502-363-1165
Email: phall@familyallergy.com

Summary: A study for subjects ages 12 years and older with asthma.
The purpose of this research study is to evaluate an investigational treatment for subjects with asthma. The study is being done in the US and is open to male and female subjects ages 12 years and older. Study participants will have 10 visits to a research center over approximately 1 year.
Inclusion Criteria:
· Diagnosis of asthma for at least 6 months.
· Subject is in good health with the exception of their asthma and does not have any chronic condition that may interfere with their respiratory function.
Exclusion Criteria:
· No clinically significant medical conditions or abnormalities.
· Pregnant women or women who are currently breast-feeding.
· Schedule will not allow subject to start study visits or take study medication before 10am.
Contact:
Traci Wesson
Heartland Clinical Research Inc
2219 N 91 Plaza
Omaha, NE 68134
Telephone: 402-502-9364

Summary: Asthma Study in San Francisco Now Enrolling.
The purpose of the study is to determine the safety and effectiveness of an investigational drug in treating asthma. The investigational drug is a combination of two FDA-approved drugs for the treatment of asthma.
Dean L. Rider, M.D. will conduct the study. Dr. Rider had been practicing gastroenterology in San Francisco for over twenty years.
You may be qualified to participate in the study if you:
· Are at least 18 years old.
· Reside in or around San Francisco.
· Have experienced stable mild-to-moderate asthma for over 6 months.
· Required asthma medication during prior 4 weeks.
Study Profile:
· 5 visits to physicians office over 12 weeks.
· Office visits will be conducted at 350 Parnassus Avenue in San Francisco near UCSF Medical Center.
· There is no charge for study visits, medications, tests or procedures.
· You will receive all study-related medications, exams and lab tests at no cost.
· You will receive reimbursement for your time and travel.
If you would like to learn more about this study, contact:
Julia Beal, Study Coordinator
First Clinical Research
350 Parnassus Ave., Suite 900
San Francisco, CA 94117
Telephone: 415-682-2431
Email: jbeal@firstclinical.com

To find clinical trials in your area, go to: http://www.centerwatch.com/search.asp